The effects of the main bioactive compound in garlic, allicin, on human coronary artery endothelial cells
The research revolves around studying the main bioactive compound in garlic, allicin, and its effects on human coronary artery endothelial cells. “I looked at how nitric oxide production, through the eNOS protein, was effected in normal, type I, and type II diabetics. The introduction to be structured is a discussion of each of the following topics supported by scientific references from pubmed in this order: 1. Cardiovascular Disease – Discussion of its current burden, prevalence, risks, causes, development, lifestyle choices, etc. 2. Coronary Artery Disease 3. Atherosclerosis 4. Diabetes – Discussion of Type I and Type II, how each develop, etc. 5. Vascular Endothelium – the breakdown of layers, function, Reactive Oxygen Species, etc. 6. Nitric Oxide Production through endothelial nitric oxide synthase (eNOS) 7. Cardiovascular Disease and Diabetes Interventions/Treatments – current pharmaceuticals, how they work on a cellular level 8. Allicin
